Tag: UAB

Mask Designed at UAB Can Protect You and Others From COVID While Taking Your Temperature and Pulse, Too. (No. It doesn’t do windows)

A fully transparent face mask designed by UAB’s chief innovation officer can include sensors to monitor the body’s temperature and pulse for early detection of viral infections, such as COVID-19.

The mask design features a clear plastic mouth covering and clear nose barriers, chin barriers and ergonomic looped arms that secure around a wearers’ ear, said Rubin Pillay, Ph.D., who is the chief innovation officer at UAB’s School of Medicine.

Pillay called his design “the world’s first smart mask.” Read more.

UAB Nasal Spray COVID Vaccine Showing Early Success in Animal Tests

Preclinical studies of a COVID-19 vaccine candidate at UAB show results that distinguish it from other vaccine candidates that also are in the advanced stages of clinical development, Maryland-based Altimmune announced Tuesday.

AdCOVID is a single dose, intranasal spray. In animal models at UAB, it’s use resulted in a potent T-cell response at the mucus layer of the lungs, including killer CD8+ T-cells, which can recognize and kill virally infected cells. Recent reports have suggested the importance of T-cell responses for long-term protection from COVID-19. Read more.

UAB-Linked Intranasal Coronavirus Vaccine Heads to Phase 1 Trials

The University of Alabama at Birmingham and Altimmune, a clinical-stage biopharmaceutical company, announced positive results Monday from preclinical studies of a COVID-19 vaccine candidate.

Altimmune plans to start its first Phase I safety and immunity tests of the vaccine candidate, called AdCOVID, in humans later this year.

The vaccine candidate was tested at UAB in an intranasal spray in mice. Read more.

UAB Doctors Urge People to Continue Being Cautious as COVID-19 Cases Grow

As Alabama continues marching toward a fuller reopening, the number of confirmed cases of coronavirus in the state continues marching upward.

But officials say it’s too early to determine whether the numbers are increasing because testing is increasing or more people are becoming infected.

A day after State Health Officer Scott Harris described infection numbers as “not as good as we could hope for” – which was also the same day the state had its worst COVID report card yet, posting 615 new cases and 19 deaths in a 25-hour period – a UAB doctor said Wednesday that people still need to take precautions.

“As we all know, Alabama has opened up and currently we are seeing an increase in our cases, particularly in hotspots such as Montgomery,” said epidemiologist Dr. Rachael Lee. “I believe Jefferson County had their highest number of cases yesterday that they’ve had this whole period of time and some of that may be reflective of testing. But it’s hard to tell at this stage.” Read more.

Should Gov. Ivey Loosen COVID-19 Restrictions? Not Yet, Retired UAB Public Health Professor Says

If Dr. Frank Franklin had the opportunity to tell Gov. Kay Ivey what she should do about loosening restrictions on businesses and other public places, his advice would be simple: Don’t, at least not quite yet.

The retired epidemiologist and pediatrician, now a professor emeritus of public health at UAB, is not convinced that the spread of the COVID-19 virus is under control in Alabama or neighboring states — three of which are already relaxing restrictions on reopening businesses and public spaces — and doesn’t want to see the progress made so far reversed.

Instead, Franklin is hoping that Ivey will announce on Tuesday that the state will stay the course for now but revisit the situation on a weekly basis, keeping transparency in the process at the forefront. Read more.

UAB to Test Potential COVID-19 Vaccine

The University of Alabama at Birmingham and the biopharmaceutical company Altimmune Inc. will test a potential vaccine for COVID-19, the university announced today.
Testing of the vaccine, AdCOVID, which was developed by the company based in Gaithersburg, Maryland, will begin in mice during the second quarter of this year. That phase of testing, designed to show the immune response to the drug in mice, is expected to take one to two months, UAB said in announcing the collaboration.
Read more.